已发表论文
Ectopic expression of Slc1a2 in the prefrontal cortex of sleep-deprived male mice counteracts the glutamate/GABA-glutamine dysfunction
YZhang F, Li Y, Jiang L, Wang Y, Tang Y, Ouyang B, Song G, Li X, Quan X, Li M, Wang H, Pan Z, Chen K, Zhang P. Ectopic expression of Slc1a2 in the prefrontal cortex of sleep-deprived male mice counteracts the glutamate/GABA-glutamine dysfunction. BMC Biol. 2025 Mar 26;23(1):86. doi: 10.1186/s12915-025-02161-7. PMID: 40140835; PMCID: PMC11948699.
Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments
You Y, Liu H, Yang Z, Chen Y, Yang F, Yu T, Zhang Y. Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments. Front Pharmacol. 2024 Dec 13;15:1474923. doi: 10.3389/fphar.2024.1474923. PMID: 39734402; PMCID: PMC11671261.
Dexmedetomidine accelerates photoentrainment and affects sleep structure through the activation of SCNVIP neurons
Zhang Y, Wang W, Li J, Zhao D, Shu Y, Jia X, Wang Y, Cheng X, Wang L, Cheng J. Dexmedetomidine accelerates photoentrainment and affects sleep structure through the activation of SCNVIP neurons. Commun Biol. 2024 Dec 28;7(1):1707. doi: 10.1038/s42003-024-07430-9. PMID: 39730868; PMCID: PMC11680882.
Acetate enables metabolic fitness and cognitive performance during sleep disruption
He Q, Ji L, Wang Y, Zhang Y, Wang H, Wang J, Zhu Q, Xie M, Ou W, Liu J, Tang K, Lu K, Liu Q, Zhou J, Zhao R, Cai X, Li N, Cao Y, Li T. Acetate enables metabolic fitness and cognitive performance during sleep disruption. Cell Metab. 2024 Sep 3;36(9):1998-2014.e15. doi: 10.1016/j.cmet.2024.07.019. Epub 2024 Aug 19. PMID: 39163862.
GBA-AAV mitigates sleep disruptions and motor deficits in mice with REM sleep behavior disorder
Chen Y, Xie WY, Xia D, Zhang MT, Sun YR, Duan WX, Shen Y, Wang F, Qu WM, Huang ZL, Liu CF. GBA-AAV mitigates sleep disruptions and motor deficits in mice with REM sleep behavior disorder. NPJ Parkinsons Dis. 2024 Aug 2;10(1):142. doi: 10.1038/s41531-024-00756-5. PMID: 39095359; PMCID: PMC11297138.
40 Hz light flickering facilitates the glymphatic flow via adenosine signaling in mice
Sun X, Dias L, Peng C, Zhang Z, Ge H, Wang Z, Jin J, Jia M, Xu T, Guo W, Zheng W, He Y, Wu Y, Cai X, Agostinho P, Qu J, Cunha RA, Zhou X, Bai R, Chen JF. 40 Hz light flickering facilitates the glymphatic flow via adenosine signaling in mice. Cell Discov. 2024 Aug 6;10(1):81. doi: 10.1038/s41421-024-00701-z. PMID: 39103336; PMCID: PMC11300858.
Dexmedetomidine Promotes NREM Sleep by Depressing Oxytocin Neurons in the Paraventricular Nucleus in Mice
Zhang Y, Li J, Li Y, Wang W, Wang D, Ding J, Wang L, Cheng J. Dexmedetomidine Promotes NREM Sleep by Depressing Oxytocin Neurons in the Paraventricular Nucleus in Mice. Neurochem Res. 2024 Jul 30. doi: 10.1007/s11064-024-04221-w. Epub ahead of print. PMID: 39078522.
Propofol improves sleep deprivation-induced sleep structural and cognitive deficits via upregulating the BMAL1 expression and suppressing microglial M1 polarization
Liu H, Yang C, Wang X, Yu B, Han Y, Wang X, Wang Z, Zhang M, Wang H. Propofol improves sleep deprivation-induced sleep structural and cognitive deficits via upregulating the BMAL1 expression and suppressing microglial M1 polarization. CNS Neurosci Ther. 2024 Jul;30(7):e14798. doi: 10.1111/cns.14798. PMID: 39015099; PMCID: PMC11252557.
Analysis of norepinephrine-regulated cerebral lymphatic drainage by the second near-infrared region in vivo imaging
Xi Li, Tianhao Yang, Zhongyang Zhang, Shengnan Wu, Zhen Yuan, Feifan Zhou; Analysis of norepinephrine-regulated cerebral lymphatic drainage by the second near-infrared region in vivo imaging. APL Photonics 1 July 2024; 9 (7): 070801. https://doi.org/10.1063/5.0205571
Mice harboring the T316N variant in the GABAAR γ2 subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway
Jiang YL, Xia L, Zhao JJ, Zhou HM, Mi D, Wang X, Wang YY, Song CG, Jiang W. Mice harboring the T316N variant in the GABAAR γ2 subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway. Exp Neurol. 2024 Apr 9;376:114775. doi: 10.1016/j.expneurol.2024.114775. Epub ahead of print. PMID: 38604438.
Dexmedetomidine promotes NREM sleep by depressing the neuronal activity of OXT neurons in the PVN
Zhang Y, Li J, Wang W, et al. Dexmedetomidine promotes NREM sleep by depressing the neuronal activity of OXT neurons in the PVN. Research Square; 2024. DOI: 10.21203/rs.3.rs-4207174/v1.
40 Hz light flickering promotes sleep through cortical adenosine signaling
Zhou X, He Y, Xu T, Wu Z, Guo W, Xu X, Liu Y, Zhang Y, Shang H, Huang L, Yao Z, Li Z, Su L, Li Z, Feng T, Zhang S, Monteiro O, Cunha RA, Huang ZL, Zhang K, Li Y, Cai X, Qu J, Chen JF. 40 Hz light flickering promotes sleep through cortical adenosine signaling. Cell Res. 2024 Feb 8. doi: 10.1038/s41422-023-00920-1. Epub ahead of print. PMID: 38332199.
Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner
He Y, Liu T, He Q, Ke W, Li X, Du J, Deng S, Shu Z, Wu J, Yang B, Wang Y, Mao Y, Rao Y, Shu Y, Peng B. Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner. Elife. 2023 Dec 22;12:RP92252. doi: 10.7554/eLife.92252. PMID: 38131301; PMCID: PMC10746144.
Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function
Zhu J, Chen C, Li Z, Liu X, He J, Zhao Z, He M, Nie B, Liu Z, Chen Y, Su K, Li X, Chen J, Xiang H, Xu F, Lin K, Zhang Z, Wang J. Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function. Neural Regen Res. 2023 Nov;18(11):2449-2458. doi: 10.4103/1673-5374.371370. PMID: 37282476; PMCID: PMC10360083.
Effects of propofol and sevoflurane on social and anxiety-related behaviours in sleep-deprived rats
Zhu J, Chen C, Wu J, He M, Li S, Fang Y, Zhou Y, Xu H, Sadigh-Eteghad S, Manyande A, Zheng F, Chen T, Xu F, Ma D, Wang J, Zhang Z. Effects of propofol and sevoflurane on social and anxiety-related behaviours in sleep-deprived rats. Br J Anaesth. 2023 Sep;131(3):531-541. doi: 10.1016/j.bja.2023.05.025. Epub 2023 Aug 4. PMID: 37543435.
Reducing complement activation during sleep deprivation yields cognitive improvement by dexmedetomidine
Zhai Q, Zhang Y, Ye M, Zhu S, Sun J, Wang Y, Deng B, Ma D, Wang Q. Reducing complement activation during sleep deprivation yields cognitive improvement by dexmedetomidine. Br J Anaesth. 2023 Sep;131(3):542-555. doi: 10.1016/j.bja.2023.04.044. Epub 2023 Jul 29. PMID: 37517957.
SAG treatment ameliorates memory impairment related to sleep loss by upregulating synaptic plasticity in adolescent mice
Gao C, Cao Y, He M, Zhang X, Zhong Q, Tang L, Chen T, Zhang Z. SAG treatment ameliorates memory impairment related to sleep loss by upregulating synaptic plasticity in adolescent mice. Behav Brain Res. 2023 Jul 26;450:114468. doi: 10.1016/j.bbr.2023.114468. Epub 2023 May 5. PMID: 37148913.
PER2 integrates circadian disruption and pituitary tumorigenesis
Guo L, Cen H, Weng J, He Y, Guo X, He D, Liu K, Duan S, Yang J, Zhang X, Qin Z, Wan Y, Chen Z, Wu B. PER2 integrates circadian disruption and pituitary tumorigenesis. Theranostics. 2023 Apr 29;13(8):2657-2672. doi: 10.7150/thno.82995. PMID: 37215573; PMCID: PMC10196825.
P2X7 receptor-activated microglia in cortex is critical for sleep disorder under neuropathic pain
Li T, Gao Y, He M, Gui Z, Zhao B, Cao Y, Chen T, Zhu J, Wang J, Zhong Q, Zhang Z. P2X7 receptor-activated microglia in cortex is critical for sleep disorder under neuropathic pain. Front Neurosci. 2023 Feb 3;17:1095718. doi: 10.3389/fnins.2023.1095718. PMID: 36816134; PMCID: PMC9936193.
Crossing nerve transfer drives sensory input-dependent plasticity for motor recovery after brain injury
Gao Z, Pang Z, Lei G, Chen Y, Cai Z, Zhu S, Lin W, Qiu Z, Wang Y, Shen Y, Xu W. Crossing nerve transfer drives sensory input-dependent plasticity for motor recovery after brain injury. Sci Adv. 2022 Sep 2;8(35):eabn5899. doi: 10.1126/sciadv.abn5899. Epub 2022 Aug 31. PMID: 36044580; PMCID: PMC9432844.
E4BP4 Coordinates Circadian Control of Cognition in Delirium
Chen M, Zhang L, Shao M, Du J, Xiao Y, Zhang F, Zhang T, Li Y, Zhou Q, Liu K, Wang Z, Wu B. E4BP4 Coordinates Circadian Control of Cognition in Delirium. Adv Sci (Weinh). 2022 Aug;9(23):e2200559. doi: 10.1002/advs.202200559. Epub 2022 Jun 17. PMID: 35713240; PMCID: PMC9376827.