产品
应用案例
关于我们
EN
已发表论文
Mice harboring the T316N variant in the GABAAR γ2 subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway

Jiang YL, Xia L, Zhao JJ, Zhou HM, Mi D, Wang X, Wang YY, Song CG, Jiang W. Mice harboring the T316N variant in the GABAAR γ2 subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway. Exp Neurol. 2024 Apr 9;376:114775. doi: 10.1016/j.expneurol.2024.114775. Epub ahead of print. PMID: 38604438.

Dexmedetomidine promotes NREM sleep by depressing the neuronal activity of OXT neurons in the PVN

Zhang Y, Li J, Wang W, et al. Dexmedetomidine promotes NREM sleep by depressing the neuronal activity of OXT neurons in the PVN. Research Square; 2024. DOI: 10.21203/rs.3.rs-4207174/v1.

40 Hz light flickering promotes sleep through cortical adenosine signaling

Zhou X, He Y, Xu T, Wu Z, Guo W, Xu X, Liu Y, Zhang Y, Shang H, Huang L, Yao Z, Li Z, Su L, Li Z, Feng T, Zhang S, Monteiro O, Cunha RA, Huang ZL, Zhang K, Li Y, Cai X, Qu J, Chen JF. 40 Hz light flickering promotes sleep through cortical adenosine signaling. Cell Res. 2024 Feb 8. doi: 10.1038/s41422-023-00920-1. Epub ahead of print. PMID: 38332199.

Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner

He Y, Liu T, He Q, Ke W, Li X, Du J, Deng S, Shu Z, Wu J, Yang B, Wang Y, Mao Y, Rao Y, Shu Y, Peng B. Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner. Elife. 2023 Dec 22;12:RP92252. doi: 10.7554/eLife.92252. PMID: 38131301; PMCID: PMC10746144.

Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function

Zhu J, Chen C, Li Z, Liu X, He J, Zhao Z, He M, Nie B, Liu Z, Chen Y, Su K, Li X, Chen J, Xiang H, Xu F, Lin K, Zhang Z, Wang J. Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function. Neural Regen Res. 2023 Nov;18(11):2449-2458. doi: 10.4103/1673-5374.371370. PMID: 37282476; PMCID: PMC10360083.

Effects of propofol and sevoflurane on social and anxiety-related behaviours in sleep-deprived rats

Zhu J, Chen C, Wu J, He M, Li S, Fang Y, Zhou Y, Xu H, Sadigh-Eteghad S, Manyande A, Zheng F, Chen T, Xu F, Ma D, Wang J, Zhang Z. Effects of propofol and sevoflurane on social and anxiety-related behaviours in sleep-deprived rats. Br J Anaesth. 2023 Sep;131(3):531-541. doi: 10.1016/j.bja.2023.05.025. Epub 2023 Aug 4. PMID: 37543435.

Reducing complement activation during sleep deprivation yields cognitive improvement by dexmedetomidine

Zhai Q, Zhang Y, Ye M, Zhu S, Sun J, Wang Y, Deng B, Ma D, Wang Q. Reducing complement activation during sleep deprivation yields cognitive improvement by dexmedetomidine. Br J Anaesth. 2023 Sep;131(3):542-555. doi: 10.1016/j.bja.2023.04.044. Epub 2023 Jul 29. PMID: 37517957.

SAG treatment ameliorates memory impairment related to sleep loss by upregulating synaptic plasticity in adolescent mice

Gao C, Cao Y, He M, Zhang X, Zhong Q, Tang L, Chen T, Zhang Z. SAG treatment ameliorates memory impairment related to sleep loss by upregulating synaptic plasticity in adolescent mice. Behav Brain Res. 2023 Jul 26;450:114468. doi: 10.1016/j.bbr.2023.114468. Epub 2023 May 5. PMID: 37148913.

PER2 integrates circadian disruption and pituitary tumorigenesis

Guo L, Cen H, Weng J, He Y, Guo X, He D, Liu K, Duan S, Yang J, Zhang X, Qin Z, Wan Y, Chen Z, Wu B. PER2 integrates circadian disruption and pituitary tumorigenesis. Theranostics. 2023 Apr 29;13(8):2657-2672. doi: 10.7150/thno.82995. PMID: 37215573; PMCID: PMC10196825.

P2X7 receptor-activated microglia in cortex is critical for sleep disorder under neuropathic pain

Li T, Gao Y, He M, Gui Z, Zhao B, Cao Y, Chen T, Zhu J, Wang J, Zhong Q, Zhang Z. P2X7 receptor-activated microglia in cortex is critical for sleep disorder under neuropathic pain. Front Neurosci. 2023 Feb 3;17:1095718. doi: 10.3389/fnins.2023.1095718. PMID: 36816134; PMCID: PMC9936193.

Crossing nerve transfer drives sensory input-dependent plasticity for motor recovery after brain injury

Gao Z, Pang Z, Lei G, Chen Y, Cai Z, Zhu S, Lin W, Qiu Z, Wang Y, Shen Y, Xu W. Crossing nerve transfer drives sensory input-dependent plasticity for motor recovery after brain injury. Sci Adv. 2022 Sep 2;8(35):eabn5899. doi: 10.1126/sciadv.abn5899. Epub 2022 Aug 31. PMID: 36044580; PMCID: PMC9432844.

E4BP4 Coordinates Circadian Control of Cognition in Delirium

Chen M, Zhang L, Shao M, Du J, Xiao Y, Zhang F, Zhang T, Li Y, Zhou Q, Liu K, Wang Z, Wu B. E4BP4 Coordinates Circadian Control of Cognition in Delirium. Adv Sci (Weinh). 2022 Aug;9(23):e2200559. doi: 10.1002/advs.202200559. Epub 2022 Jun 17. PMID: 35713240; PMCID: PMC9376827.